Bio-Med Ideas

April 27, 2014

Mechanistic insight into Hypoxia-induced tumorigenesis, invasion and metastasis: HIF-1α suppresses the expression of DNA repair protein hMSH2 via up regulation of its target miRNA, 27/April/2014, 22.24

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Web: http://genomediscovery.org Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ To cite: Boominathan, Mechanistic insight into Hypoxia-induced tumorigenesis, invasion and metastasis: HIF-1α suppresses the expression of DNA […]
April 27, 2014

Mechanistic insight into Hypoxia-induced tumorigenesis, invasion and metastasis: HIF-1α suppresses the expression of tumor suppressor TPM1 via up regulation of its target miRNA, 27/April/2014, 22.20

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Web: http://genomediscovery.org Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ To cite: Boominathan, Mechanistic insight into Hypoxia-induced tumorigenesis, invasion and metastasis: HIF-1α suppresses the expression of tumor […]
April 27, 2014

Insights into the regulation of Contractility of heart muscle cells: The arthritis drug Withaferin A (WFA) suppresses the expression of Mitochondrial Calcium Uniporter (MCU) via up regulation of its target gene, 27/April/2014, 16.44

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Web: http://genomediscovery.org Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ To cite: Boominathan, Insights into the regulation of Contractility of heart muscle cells: The arthritis drug Withaferin A […]
April 27, 2014

Natural Product-based anti-cancer therapy: Curcumin, the major component of Turmeric, eradicates cancer by suppressing the expression of nucleotide sanitizing enzyme MTH1/NUDT1, 27/April/2014, 16.16

A study from Karolinska Institutet, Stockholm, Sweden shows that MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool.  This study was published in the April 10, 2014 Nature by Prof. Dr […]
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