Bio-Med Ideas

April 14, 2019

Mechanistic insights into why premenopausal women have lower incidence of TIIDM: Estradiol/17-β Estradiol-based therapy for Diabetes Mellitus: Estradiol/17-β Estradiol augments the expression of FGF19 and FGF1,  attenuates hepatic glucose production, decreases hepatic acetyl CoA content, brings down the levels of plasma ACTH, and corticosterone, augments insulin sensitivity, promotes weight loss and alleviates TIDM, via upregulation of its target gene, 14/April/2019, 8.24 am

Introduction: What they say  A study from Diabetes and Obesity Center of Excellence, Department of Medicine, University of Washington, Seattle, Washington, USA shows that Central injection […]
April 14, 2019

Ribonucleic acid-based combination therapy for Diabetic retinopathy: A pharmaceutical mixture encompassing  LncRNA MEG3, Epicatechin and Matrine (MEG3EM)  inhibits Soluble epoxide hydrolase (sEH) expression, decreases toxic 19,20-dihydroxydocosapentaenoic acid levels, inhibits pericyte loss, vascular permeability, and inflammation of the eye and progression of diabetic retinopathy, via down regulation of its target gene, 14/April/2019,  6.23 am

Introduction: What they say A study from the Institute for Vascular Signalling, Centre for Molecular Medicine, Goethe University, Frankfurt am Main, Germany; and German Centre for […]
April 13, 2019

Embryo-derive peptide may aid in the treatment of muscle atrophy and wasting:  Synthetic Preimplantation factor (sPIF) increases the expression of FGF19 and its receptor ß-Klotho, phosphorylates ERK1/2 and S6K1, decreases the expression of tumor suppressors  genes, promotes regeneration of muscle cells and hypertrophy of skeletal muscle, and reverses muscular atrophy and wasting via upregulation of its target gene, 14/April/2018, 12.09 am

Introduction: What they say A study from Department of Biology, University of Bergen, Bergen, Norway; and Univ-Lyon, CarMeN Laboratory, INSERM 1060, INRA 1397, Université Claude Bernard […]
April 13, 2019

Oats-derived compound functions as an anti-HIV agent: A pharmaceutical mixture encompassing Avenanthramide-A  increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production, via upregulation of its target gene, 13/April/2019, 11.56 pm

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that:  Oats-derived compound functions as an anti-HIV agent: A pharmaceutical mixture encompassing Avenanthramide-A  increases Heme oxygenase 2 […]
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