Bio-Med Ideas

March 23, 2018
Published by admin_auro at March 23, 2018
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Sugar-based anti-ageing and Lifespan extension therapy:  Rebaudioside A, a natural sweetener, increases CHIP levels, increases monoubiquitylation of insulin receptor (INSR), decreases INSR protein levels and enhances lifespan via down regulation of its target gene, 24/March/2018, 1.10 am

Introduction: What they say  A study from Institute for Cell Biology, University of Bonn, Ulrich-Haberland Str.  Bonn, Germany; and Institute for Genetics and CECAD Research Center, […]
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March 23, 2018
Published by admin_auro at March 23, 2018
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Sugar-based therapy for diabetes (TIIDM): D-Fagomine, an iminosugar isolated from mulberry leaves, among others, increases GLP1R and Caveolin-1 (CAV-1) expression, promotes glucose-induced insulin secretion, improves insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM, via up regulation of its target gene, 24/March/2018, 12.55 am

Introduction: What they say A study from the Comprehensive Diabetes Center and Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Alabama at Birmingham, […]
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March 23, 2018
Published by admin_auro at March 23, 2018
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A sweet way to decrease blood pressure/sugar and extend lifespan: Sugar-based Lifespan extension therapy: Lactulose (brand name: Cholac, Generlac, Consulose, Duphalac) , a non-absorbable sugar that aids in the treatment of constipation and hepatic encephalopathy,  prolongs mammalian life span, via down regulation of angiotensin II type I receptor (AT1R), 24/March/2018, 12.41 am

Significance of the study: It has been shown earlier that antagonizing angiotensin II type I receptor (AT1R) expression may prolong mammalian life span. Further, it has been shown […]
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March 23, 2018
Published by admin_auro at March 23, 2018
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Molecular  therapy for Non-alcoholic fatty liver disease (NAFLD): Melatonin promotes degradation of HMGCR, decreases the levels of triglycerides, free cholesterol, and total cholesterol and prevents the progression of Non-alcoholic fatty liver disease (NAFLD via down regulation of its target gene, 24/March/2018, 12.32 am

Significance of the study: Given that: (1)  15-30% of Western populations suffer from Non-alcoholic fatty liver disease (NAFLD), while 6-25% of Asian populations suffer from it; (2) 75 to […]
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