Bio-Med Ideas

March 2, 2018
Published by admin_auro at March 2, 2018
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Molecular therapy for tuberculosis: Triclosan, an antibacterial and antifungal agent found commonly in toothpastes, soaps, among others, deacetylates RelA/p65, inhibits inflammatory gene expression downstream of RelA/p65, inhibits TB pathogenesis, increases the efficacy of anti-TB drug, and promotes M. tuberculosis clearance via up regulation of its target gene, 2/March/2018, 8.06 am

Introduction: What they say: A study from the Singapore Immunology Network, Agency for Science, Technology and Research, Singapore; and Lee Kong Chian School of Medicine, Nanyang […]
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March 2, 2018
Published by admin_auro at March 2, 2018
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Polyamine-based Lifespan extension therapy:  Spermidine increases life span via up-regulation of its target gene BubR1, 2/March/2018, 7.55 am

 What they say: Introduction:  A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston,USA; and […]
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March 2, 2018
Published by admin_auro at March 2, 2018
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Small-molecule based therapy for autoimmune diabetes (TIDM): Sarcocine (N-Methyl Glycine) , a derivative of amino acid glycine, increases PD-L1 expression, increases Tregs function, promotes immune tolerance, increases pancreatic β-cell proliferation and regeneration, increases insulin secretion, improves insulin sensitivity, increases energy utilization, and reverses TIDM, via up regulation of its target gene, 2/March/2018, 7.33 am

Introduction: What they say A study from the International Center for T1D, Pediatric Clinical Research Center Romeo ed Enrica Invernizzi, “L. Sacco” Department of Biomedical and […]
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March 2, 2018
Published by admin_auro at March 2, 2018
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Molecular therapy for body weight control, energy homeostasis and TIIDM: Spermidine, an endogenous polyamine, inhibits DNA methyltransferase 3a (Dnmt3a) expression, increases FGF21 expression, augments insulin sensitivity, increases glucose tolerance, and protects from diet-induced obesity and TIIDM, via up regulation of its target gene, 2/March/2018, 7.17 am

Introduction: What they say  A study from Nutritional Sciences and Toxicology Department, University of California, Berkeley, Berkeley, United States shows that “Dnmt3a is an epigenetic mediator […]
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