Bio-Med Ideas

February 16, 2018

Molecular therapy for Cancer: A therapeutic mix encompassing N-Acetyl Cysteine (NAC),  SAHA, Amitriptyline, 17-DMAG and Rosuvastatin (NSADR) increases the expression of REV-ERBa, inhibits glioblastoma proliferation, increases interferon-IFNγ signalling, increase antigen presentation and unfolding response, increases Cytotoxic activity of T-cells, decreases tumor burden and increases survival, via up-regulation of its target gene, 16/February/2017, 11.04 pm

Introduction:What they say: A recent study from Regulatory Biology Laboratory, Salk Institute for Biological Studies, La Jolla, California 92037, USA and Laboratory of Genetics, Salk Institute […]
February 16, 2018

Laminar shear stress-based therapy for autoimmune diabetes (TIDM): Laminar shear stress increases PD-L1 expression, augments Tregs function, promotes immune tolerance, increases pancreatic β-cell proliferation and regeneration, increases insulin secretion, improves insulin sensitivity, increases energy utilization, and reverses TIDM, via up regulation of its target gene, 16/February/2018, 7.13 am

Introduction: What they say A study from the International Center for T1D, Pediatric Clinical Research Center Romeo ed Enrica Invernizzi, “L. Sacco” Department of Biomedical and […]
February 16, 2018

Molecular therapy for ageing-associated diseases and Lifespan extension: Rolipram, an experimental drug used in the treatment of depression and others, increases NMN/NAD levels, decreases interaction of DBC1 with PARP1, increases PARP1 activity, promotes DNA repair, augments tolerance against radiation, cancer and aging via down regulation of its target gene, 16/February/2018, 7.01 am

Introduction: What they say A study from Department of Genetics, Paul F. Glenn Center for the Biology of Aging, Harvard Medical School, Boston, MA, USA; and […]
February 16, 2018

Vitamin-based therapy for glucose homeostasis and TIIDM: A pharmaceutical mixture encompassing Pyridoxamine and Sulforaphane increases Pax6 and insulin expression, decreases the levels of glucagon, ghrelin and Somatostatin, reduces metabolic stress, improves insulin sensitivity, promotes glucose homeostasis and prevents progression to TIIDM via down regulation of its target gene, 16/February/2018, 6.48 am

Introduction: What they say A study from the Department of Developmental Biology and Cancer Research, The Institute for Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, […]
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