Bio-Med Ideas

April 27, 2019

Empty-stomach intelligence is explained: Mechanistic insights into how hunger hormone Ghrelin augments augments memory, learning, and cognition:  Ghrelin, a digestive hormone that controls appetite,  increases Tissue inhibitor of metalloproteinases 2 (TIMP2) and BDNF levels, improves cognition, and attenuates age-associated decline in memory and learning, via up-regulation of its target genes, 28/April/2018, 12.17 am

Introduction: What they say A study from Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California 94305, USA;  Paul F. Glenn Center […]
April 27, 2019

Natural product-based therapy for anxiety and depression: Paeonol, isolated from Paeonia suffruticosa,  decreases PHF8 levels, increases the expression of serotonin receptors Htr1a and Htr2a, and promotes resistance to stress-induced -anxiety and -depression, via down-regulation of its target gene, 27/April/2019, 12.05 am

Introduction: What they say:  A study from Department of Molecular Biology, Cancer Center and Center for Regenerative Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA; Department […]
April 27, 2019

Hunger hormone-based therapy for lowering cholesterol, and triglycerides levels: Ghrelin, a digestive hormone that controls appetite, decreases the levels of HMGCR,  triglycerides, free cholesterol, and total cholesterol and prevents the progression of Non-alcoholic fatty liver disease (NAFLD), via up-regulation of its target gene, 27/April/2019, 11.57 pm

The significance of the study: Given that: (1)  15-30% of Western populations suffer from Non-alcoholic fatty liver disease (NAFLD), while 6-25% of Asian populations suffer from it; (2) 75 […]
April 27, 2019

PIM-1-based Regenerative therapy for regaining the lost cardiomyocytes in Myocardial patients: PIM-1, a regulator of cell cycle progression, increases the expression of ERBB2/Her2 and promotes dedifferentiation  of cardiomyocytes, via up-regulation of its target gene, 27/April/2019, 11.40 pm

Introduction: What they say A recent study from the Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel shows that “ERBB2 triggers mammalian heart regeneration by promoting cardiomyocyte dedifferentiation and proliferation.” This study was […]
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