Bio-Med Ideas

January 8, 2018

Molecular therapy for Metastatic cancers: Torasemide, an anti-hypertensive drug, increases the expression of tumor/metastasis suppressors CCM3/KRIT1 and TIMP3, inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up regulation of its target gene, 8/January/2017, 10.48 pm

From Significance of the study to Public health relevance: Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more […]
January 8, 2018

Lifespan extension therapy: Tomatidine, isolated from unripe tomato, among others, prolongs mammalian life span via down regulation of angiotensin II type I receptor (AT1R), 8/January/2017, 10.41 pm

Significance of the study: It has been shown earlier that antagonizing angiotensin II type I receptor (AT1R) expression may prolong mammalian life span. Further, it has been shown […]
January 8, 2018

Combinatorial therapy for TIIDM: A pharmaceutical mixture encompassing D-Serine and Folic acid (SFA) augments the expression of FGF19 and FGF1,   attenuates hepatic glucose production, decreases hepatic acetyl CoA content, brings down the levels of plasma ACTH, and corticosterone, augments insulin sensitivity, promotes weight loss and alleviates TIIDM via up regulation of its target gene, 8/January/2017, 10.30 pm

Introduction: What they say A study from Diabetes and Obesity Center of Excellence, Department of Medicine, University of Washington, Seattle, Washington, USA shows that Central injection […]
January 8, 2018

Molecular therapy for body weight control, energy homeostasis and TIIDM: Berberine, isolated from Berberis, among others, inhibits DNA methyltransferase 3a (Dnmt3a) expression, increases FGF21 expression, augments insulin sensitivity, increases glucose tolerance, and protects from diet-induced obesity and TIIDM, via up regulation of its target gene, 8/January/2017, 10.19 am

Introduction: What they say A study from Nutritional Sciences and Toxicology Department, University of California, Berkeley, Berkeley, United States shows that “Dnmt3a is an epigenetic mediator […]
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