Bio-Med Ideas

December 27, 2017

Molecular therapy for pulmonary arterial hypertension: Azilsartan[Brand name: Edarbi], an angiotensin II type 1 receptor blocker used in the treatment of high blood pressure, inhibits the development of pulmonary arterial hypertension via down regulation of its target gene Notch3, 28/December/2017, 12.44 am

What they say:  A study from the University of California, La Jolla, California, USA shows that “Notch3 signaling promotes the development of pulmonary arterial hypertension.” This study was published in the 15 November  2009 issue of the journal “Nature Medicine”[the number […]
December 26, 2017

Natural product therapy for body weight control, energy homeostasis and TIIDM:Lycopene, isolated from Gac, Guava and Tomatoes,  decreases CADM1 and its downstream target genes that promote glucose-induced insulin secretion, improves insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM via up regulation of its target gene, 27/December/2017, 12.20 am

Introduction: What they say A study from the Max Delbrück Center for Molecular Medicine, Berlin, Germany shows that “Regulation of body weight and energy homeostasis by […]
December 26, 2017

Natural product-based therapy for TIIDM: A pharmaceutical mixture encompassing Carnosic acid, Lycopene, Ferulic acid, and Glycyrrhizic acid (CALFAG) augments the expression of FGF19 and FGF1,   attenuates hepatic glucose production, decreases hepatic acetyl CoA content, brings down the levels of plasma ACTH, and corticosterone, augments insulin sensitivity, promotes weight loss and alleviates TIIDM via up regulation of its target gene, 26/December/2017, 11.59 pm

Introduction: What they say A study from Diabetes and Obesity Center of Excellence, Department of Medicine, University of Washington, Seattle, Washington, USA shows that Central injection […]
December 26, 2017

Regenerative therapy for regaining the lost cardiomyocytes in Myocardial patients:  A pharmaceutical mixture [PMEET] encompassing Pyridoxamine (PM-a form of Vitamin-B (6)) and 14, 15 Epoxyeicosatrienoic acid (14, 15-EET)  increases the expression of ERBB2/Her2 and promotes dedifferentiation  of cardiomyocytes via down regulation of its target gene, 26/December/2017, 11.49 pm

Introduction: What they say A recent study from the Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel shows that “ERBB2 triggers mammalian heart regeneration by promoting cardiomyocyte dedifferentiation and proliferation.” This study was […]
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