Bio-Med Ideas

March 12, 2019

Repurposing the antihyperlipidemic drug Atorvastatin into an anti-HIV agent: Atorvastatin (trade name: Lipitor), a medication prescribed to lower cholesterol and triglyceride, increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production, via upregulation of its target gene, 12/March/2019, 9.51 am

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Repurposing the antihyperlipidemic drug Atorvastatin into an anti-HIV agent: Atorvastatin (trade name: Lipitor), a medication prescribed to […]
March 12, 2019

Probiotic-based immune enhancement therapy: Probiotic Clostridium butyricum MIYAIRI 588 (CBM588) increases SOX2 expression, and promotes innate immunity against bacterial infection, via down-regulation of its target gene, 12/March/2019, 9.41 am

Introduction: What they say:   A recent study from the Institute of Biophysics, Chinese Academy of Sciences, Beijing, China shows that “Sox2 functions as a sequence-specific DNA sensor in […]
March 12, 2019

Ribonucleic acid-based therapy for Diabetes Mellitus: LncRNA H19 augments the expression of FGF19 and FGF1,  attenuates hepatic glucose production, decreases hepatic acetyl CoA content, brings down the levels of plasma ACTH, and corticosterone, augments insulin sensitivity, promotes weight loss and alleviates TIDM, via upregulation of its target gene, 12/March/2019, 9.27 am

Introduction: What they say  A study from Diabetes and Obesity Center of Excellence, Department of Medicine, University of Washington, Seattle, Washington, USA shows that Central injection […]
March 12, 2019

Ribonucleic acid-based therapy for enhancing memory and cognition: LncRNA PVT1 increases Tissue inhibitor of metalloproteinases 2 (TIMP2) levels, improves cognition, and decreases age-associated decline in memory and learning, via down-regulation of its target genes, 12/March/2019, 9.18 am

Introduction: What they say: A study from Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California 94305, USA;  Paul F. Glenn Center […]
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