Bio-Med Ideas

April 11, 2017

Natural product derived-therapy for Regenerating the lost pancreatic β-cells in Diabetic patients: Lucidone, found in Lindera Erythrocarpa, increases the expression of IGF1R, INSR, and IRS2, and promotes an insulin-sensitized state via up-regulation of its target, 11/April/2017, 10.26 pm

Introduction: What they say:  A study from the Stem Cell Transplantation Program, Division of Pediatric Hematology/Oncology, Boston Children’s Hospital and Dana-Farber Cancer Institute, Boston, Massachusetts, USA shows that “The […]
April 11, 2017

Natural product-derived therapy for Metastatic cancers: γ-Bisabolene, found in Cardamom, Cubeb pepper and Oregano among others, decreases the expression of metastasis promoters ZBTB2 and PPM1F, inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up regulation of its target gene, 11/April/2017, 6.36 am

From Significance of the study to Public health relevance: Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more […]
April 10, 2017

Natural product-derived therapy for prostate cancer bone metastasis: Kukoamine A (KuA), a spermine alkaloid derived from Cortex lycii radicis and Lycium chinense among others, inhibits the expression of Monoamine oxidase A (MAOA), inhibits Shh-IL6-RANKL signaling network, suppresses tumor-stromal interactions, reduces prostate cancer metastasis and prolongs survival via up regulation of its target gene, 11/April/2017, 12.01 am

Introduction: What they say: A study from the Uro-Oncology Research Program, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA shows that “MAOA-Dependent Activation of […]
April 10, 2017

Natural product-derived therapy for Human cancers: α-Lipoic acid, found in leafy green vegetables, increases the expression of mitochondrial protein LACTB, decreases levels of mitochondrial phosphatidylserine decarboxylase, alters mitochondrial lipid metabolism, and promotes differentiation of breast cancer cells via up-regulation of its target gene, 10/April/2017, 11. 45 pm

Introduction: What they say: A study from the Whitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge, Massachusetts, USA, Department of Biology, Massachusetts Institute of Technology, […]
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