Bio-Med Ideas

April 10, 2017

Natural product-derived therapy for Allergic rhinitis:Dioscin, a natural steroid saponin, inhibits GM-CSF, Interleukin 13 receptor(IL-13)-Rα1, and eotaxin expression, among others, inhibits mucus production and alleviates allergic rhinitis via up regulation of its target gene, 10/April/2017, 11.29 pm

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Natural product-derived therapy for Allergic rhinitis: Dioscin, a natural steroid saponin,  inhibits GM-CSF, Interleukin 13 receptor(IL-13)-Rα1, […]
April 10, 2017

Natural product-derived regenerative therapy for reversing diabetes: Berberine, found in Berberis, Oregon grape, Hydrastis canadensis, and Phellodendron amurense among others, increases the expression of Sox17, Sox2, Pdx-1, and Ngn3, decreases mTOR expression, promotes regeneration of insulin-producing ß cells, increases insulin secretion, promotes glucose homeostasis and reverses T1D and T2D via down regulation of its target gene, 10/April/2017, 11.18 pm

Introduction: What they say A study from the Longevity Institute, School of Gerontology, Department of Biological Sciences, University of Southern California, 3715 McClintock Avenue, Los Angeles, […]
April 10, 2017

Amino-acid based therapy for tuberculosis:L-Leucine, a branched-chain amino acid (BCAA), deacetylates RelA/p65, inhibits inflammatory gene expression downstream of RelA/p65, inhibits TB pathogenesis, increases the efficacy of anti-TB drug, and promotes M. tuberculosis clearance via up regulation of its target gene, 10/April/2017, 10.45 pm

Introduction: What they say: A study from the Singapore Immunology Network, Agency for Science, Technology and Research, Singapore; and Lee Kong Chian School of Medicine, Nanyang […]
April 10, 2017

Natural product-derived therapy for glucose homeostasis and TIIDM: Mangiferin (MA), found in Mangoes and Iris Unguicularis among others, increases Pax6 and insulin expression, decreases the levels of glucagon, ghrelin and Somatostatin, reduces metabolic stress, improves insulin sensitivity, promotes glucose homeostasis and prevents progression to TIIDM via down regulation of their target gene, 10/April/2017, 11.35 am

Introduction: What they say  A study from the Department of Developmental Biology and Cancer Research, The Institute for Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, […]
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