Bio-Med Ideas

May 22, 2017

Vitamin-based therapy for pulmonary arterial hypertension: Cholecalciferol (a form of Vitamin-D) inhibits the development of pulmonary arterial hypertension via down regulation of Notch3 and its target gene Hes-5, 22/May/2017, 9.53 am

What they say:  A study from the University of California, La Jolla, California, USA shows that “Notch3 signaling promotes the development of pulmonary arterial hypertension.” This study was published in the 15 November  2009 issue of the journal “Nature Medicine”[the number […]
May 22, 2017

Anti-telomerase cancer therapy: Metformin, the widely used drug in the treatment of TIIDM, suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) and the cellular immortality gene telomerase and inhibits cancer progression via down-regulation of it target gene, 22/May/2017, 9.23 am

Introduction: What they say:   The 1989 Nobel prize winner in Chemistry, Prof. Thomas R. Cech from the BioFrontiers Institute, USA has published a research paper in the 13 December 2012 issue of the Nature journal (492(7428):285-9; and I.F: >42) stating that “The TEL […]
May 22, 2017

Natural product-derived therapy for Metastatic cancers: Myrtenal, found in Cardamom, decreases the expression of metastasis promoters ZBTB2 and PPM1F, inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up regulation of its target gene, 22/May/2017, 8.51 am

From Significance of the study to Public health relevance: Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more […]
May 22, 2017

Music-based regenerative therapy for improving memory in aged individuals: Music therapy increases Tissue inhibitor of metalloproteinases 2 (TIMP2) levels, improves cognition, and decreases age-associated decline in memory and learning via down regulation of its target genes, 22/May/2017, 8.45 am

Introduction: What they say A study from Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California, USA;  Paul F. Glenn Center for […]
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