Bio-Med Ideas

February 11, 2017

Natural product therapy for pulmonary arterial hypertension: Cucurbitacin E, one of the main components of Watermelon, inhibits the development of pulmonary arterial hypertension via down regulation of its target gene Notch3, 11/February/2017, 9.37 am

What they say:  A study from the University of California, La Jolla, California, USA shows that “Notch3 signaling promotes the development of pulmonary arterial hypertension.” This study was published in the 15 November  2009 issue of the journal “Nature Medicine”[the number […]
February 11, 2017

Natural product/vitamin-based Combination therapy for PTEN-deficient cancer: Combination of Linalool, Cholecalciferol and ATRA decreases the expression of the CHD1, increases the expression of a number of tumor suppressor genes, inhibits pro-survival TNF-NF-kB gene network, and suppresses tumorigenesis of PTEN-deficient cancer, 11/February/2017, 8.54 am

Introduction: What they say: A study from the Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA shows that […]
February 11, 2017

Natural product-derived PD-L1 pathway blockade enhances the efficacy of Cancer immunotherapy: Paeonol (2′-hydroxy-4′-methoxy Acetophenone), isolated from Paeonia Suffruticosa Andrews, inhibits the expression of PD-L1, inhibits inflammatory signalling and the number of tumor-infiltrating lymphocytes and macrophages, increases Cytotoxic activity of T-cells, decreases tumor burden and increases survival via up-regulation of its target gene, 11/February/2017, 6.50 am

Introduction:What they say: A recent study from Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Unit 108, 1515 Holcombe Boulevard, […]
February 11, 2017

Natural product-derived therapy for Myocardial Infarction: Rice bran protein hydrolysates (RBPs) inhibit DNA damage responses, induce telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction via up-regulation of PNUTS, 11/February/2017, 6.37 am

What they say:  A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the 7 March  2013 issue of Nature  by Prof Dimmler, […]
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