Bio-Med Ideas

March 16, 2019

Ribonucleic acid-based therapy for glaucoma:  LncRNA DGCR5 increases Nmnat1 expression, increases NAD+ levels, improves neuronal dysfunction, and protects against glaucoma,  via down regulation of its target gene, 16/March/2019, 5.30 am

Introduction: What they say A study from the The Jackson Laboratory, Bar Harbor, ME 04609, USA; Department of Ophthalmology, Tufts University of Medicine, Boston, MA 02111, […]
March 15, 2019

Epicatechin-3-gallate(ECG)-based antiviral therapy for chikungunya (CHIKV) and Zika (ZIKV) viruses: Epicatechin-3-gallate(ECG), one of the main components of green tea, increases spermidine/spermine N1-acetyltransferase (SAT) expression, depletes spermidine and Spermine levels, and restricts Chikungunya and Zika viruses replication via upregulation of its target gene, 16/March/2019, 5.23 am

Introduction: What they say A study from the Viral Populations and Pathogenesis Unit, Institut Pasteur, CNRS UMR 3569, 25–28 rue du Dr. Roux, 75724 Paris Cedex […]
March 14, 2019

Molecular therapy for Anti-ageing and Lifespan extension: Sitagliptin (brand name: Januvia), an anti-hyperglycemic drug,  increases CHIP levels, increases monoubiquitylation of insulin receptor (INSR), decreases INSR protein levels and enhances lifespan via down regulation of its target gene, 14/March/2018, 11.12 pm

Introduction: What they say A study from Institute for Cell Biology, University of Bonn, Ulrich-Haberland Str.  Bonn, Germany; and Institute for Genetics and CECAD Research Center, […]
March 14, 2019

Ribonucleic acid-based Lifespan extension therapy: A therapeutic mix encompassing lncRNA-TUG1 and/or Ursolic acid, Maresin, DIM, Ursolic acid  Lutein, Maresin, Cholecalciferol, Catalpol, Isoliquiritigenin (UMDULMCCI)  activates autophagy, promotes leanness, increases insulin sensitivity, improves motor function, alleviates ageing feature and extends lifespan via upregulation of its target gene ATG5 (Autophagy-related 5), 14/March/2018, 11.01 pm

Introduction: What they say A study from the Global Research Laboratory, Seoul National University, Korea shows that “Overexpression of Atg5 in mice activates autophagy and extends lifespan.” This study was […]
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