Bio-Med Ideas

May 16, 2019

Natural sugar-based therapy targeting cancer stem cells and immune-inhibitory receptors in advanced metastatic cancers: A pharmaceutical mixture encompassing a pharmacological formulation encompassing Xylobiose (a disaccharide of xylose, with a  a beta-1,4-bond), and probiotic Lactobacillus rhamnosus increases the expression of tumor suppressor genes, such as  p57Kip2, p12DOC1, E-cadherin, p53, and TA-p73/p63, stalls cell cycle progression, inhibits immune-inhibitory receptors/molecules, suppresses cancer stem cell proliferation, inhibits migration, invasion and metastasis of cancer cells, confers protection against chemoresistance and prolongs survival, via up-regulation of its target gene, 16/May/2019, 10.39 pm

What we say: On the foundation of this interesting finding, Dr L Boominathan PhD, the Director-cum-chief Scientist of GBMD, reports that:  Natural sugar-based therapy targeting cancer […]
May 16, 2019

Carvacrol as a broad-spectrum anti-infective agent:  Carvacrol, one of the main components of Origanum vulgare, Thyme, Lipidium & Lavandula multifida,  inhibits Hepatitis-B/C, Dengue, Zika, Ebola, HIV-1, Mtb, Malaria, CMV, Influenza H1NI1,  respiratory syncytial,  Sindbis, and SFV viruses by increasing the Levels of the Antiviral Proteins IFITM3, & Interferon-stimulated gene 15, 16/May/2019,  10.27 pm

Introduction: What they say: A study from the Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard Medical School, Charlestown, MA 02129, USA […]
May 15, 2019

Mixing coffee with tea does not appear to be a tasty idea, but it will decrease lipid levels and protect against Non-alcoholic fatty liver disease (NAFLD): A pharmaceutical mixture encompassing Caffeine and catechins decreases the levels of HMGCR,  triglycerides, free cholesterol, and total cholesterol and decelerates the progression of NAFLD, via up-regulation of its target gene, 15/May/2019, 12.08 am

The significance of the study: Given that: (1)  15-30% of Western populations suffer from Non-alcoholic fatty liver disease (NAFLD), while 6-25% of Asian populations suffer from it; (2) 75 […]
May 15, 2019

Intracardiac/epicardial injection of Carvedilol protects against & promotes repair & functional recovery after Myocardial Infarction: Carvedilol (brand name: Coreg) , used to treat high blood pressure, congestive heart failure, left ventricular dysfunction and others, inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction, via up-regulation of its target gene, 15/May/2019, 11.47 pm

What they say:  A recent study from the Molecular Medicine Laboratory, International Centre for Genetic Engineering and Biotechnology (ICGEB), a United Nations organisation in Trieste, Trieste, Italy, School […]
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