Bio-Med Ideas

March 2, 2017

Amino acid based therapy for glucose homeostasis and TIIDM: Leucine, an essential amino acid found abundantly in parmesan cheese, soy, and hemp seeds and among others, increases Barr2 expression, augments the functional activity of CAMKII, increases insulin secretion, promotes glucose homeostasis, prevents progression to TIIDM and ameliorates obesity-associated metabolic deficits via down regulation of its target gene, 2/March/2017, 10.29 pm

Introduction: What they say A study from the Molecular Signaling Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland […]
March 2, 2017

Natural product-derived therapy for Myocardial Infarction: Withaferin A (WA), isolated from Ashwagantha, inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction via up regulation of PNUTS, 2/March/2017, 7.21 pm

What they say:  A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the 7 March  2013 issue of Nature  by Prof Dimmler, […]
March 2, 2017

Anti-telomerase cancer therapy: Ginkgolic acid C 17:1 (GAC 17:1), isolated from Ginkgo biloba leaves, suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) and the cellular immortality gene telomerase and inhibits cancer progression via down-regulation of it target gene, 2/March/2017, 6.51 pm

Introduction: What they say:   The 1989 Nobel prize winner in Chemistry, Prof. Thomas R. Cech from the BioFrontiers Institute, USA has published a research paper in the 13 December 2012 issue of the Nature journal (492(7428):285-9; and I.F: >42) stating that “The TEL […]
March 2, 2017

Natural product-based therapy for Metastatic cancers: Hyperoside, isolated from Drosera rotundifolia, and Common self-heal, among others, increases the expression of TIMP3 and inhibits migration, invasion and metastasis of cancer cells via down regulation of its target gene, 2/March/2017, 10.53 am

Research findings to Therapeutic opportunity:  A number of studies suggest that Hyperoside functions as an anticancer agent. However, the mechanism of action is far from clear. […]
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