Bio-Med Ideas

March 6, 2017

Natural product-derived therapy for metastatic prostate cancer: 6-gingerol , isolated from Ginger, inhibits the expression of CDC42, CDC42EP3, RAC1 and ARPC5, and GAS6, suppresses the expression of stem cell molecules CD44 and EZH2, promotes epithelial phenotype, suppresses tumorigenesis, migration, invasion, stem cell regeneration and metastasis via up regulation of its target gene, 6/March/2017, 11.14 pm

Introduction: What they say: A study from the Department of Epigenetics and Molecular Carcinogenesis, University of Texas MD Anderson Cancer Center, Science Park, Texas 78957, USA […]
March 6, 2017

Natural product-derived antiviral therapy for HIV virus: Calycosin, the major isoflavonoid found in Radix astragali, Trifolium pratense, and Astragalus Membranaceus (fisch)Bge, increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production via up regulation of its target gene, 6/March/2017, 10.34 pm

Introduction: What they say A study from the Department of Biochemistry and Molecular Biophysics and Department of Microbiology and Immunology, Howard Hughes Medical Institute, Columbia University, […]
March 6, 2017

Natural product-derived therapy for Hepatocellular carcinoma: Eriocitrin, one of the components in Lemons, attenuates phosphoenolpyruvate carboxykinase (PEPCK1) sumoylation, stabilizes PEPCK1 levels, promotes gluconeogenesis, inhibits glycolysis and attenuates the progression of hepatocellular carcinoma via up regulation of its target gene, 6/March/2017, 3.24 pm

Introduction: What they say: A study from the State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen […]
March 6, 2017

Molecular therapy for Metastatic cancers: 2-Iodohexadecanal (2-IHDA) decreases the expression of PPM22 and inhibits migration, invasion and metastasis of cancer cells via up regulation of its target gene, 6/March/2017, 9.34 am

From Significance of the study to Public health relevance: Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more […]
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