Bio-Med Ideas

March 4, 2017

Vitamin-based therapy for metastatic prostate cancer: Cholecalciferol inhibits the expression of CDC42, CDC42EP3, RAC1 and ARPC5, and GAS6, suppresses the expression of stem cell molecules CD44 and EZH2, promotes epithelial phenotype, suppresses tumorigenesis, migration, invasion, stem cell regeneration and metastasis via up regulation of its target gene, 4/March/2017, 11.17 pm

Introduction: What they say: A study from the Department of Epigenetics and Molecular Carcinogenesis, University of Texas MD Anderson Cancer Center, Science Park, Texas 78957, USA […]
March 4, 2017

Natural product-based therapy for Metastatic cancers: Hyperoside, isolated from Drosera rotundifolia, and Common self-heal, among others, increases the expression of BTG2 and inhibits migration, invasion and metastasis of cancer cells via down regulation of its target gene, 4/March/2017, 7.35 am

Research findings to Therapeutic opportunity:  A number of studies suggest that Hyperoside functions as an anticancer agent. However, the mechanism of action is far from clear. […]
March 4, 2017

Molecular therapy for Metastatic cancers: α-Solanine, isolated from Flowers and Fruits of bittersweet nightshade, decreases the expression of PPM22 and inhibits migration, invasion and metastasis of cancer cells via up regulation of its target gene, 4/March/2017, 7.21 am

From Significance of the study to Public health relevance: Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more […]
March 3, 2017

Natural product-derived antiviral therapy for HIV virus: Epigallocatechin gallate, one of the main components of Green tea, increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production via up regulation of its target gene, 3/March/2017, 11.11 pm

Introduction: What they say A study from the Department of Biochemistry and Molecular Biophysics and Department of Microbiology and Immunology, Howard Hughes Medical Institute, Columbia University, […]
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