Bio-Med Ideas

January 13, 2017

Natural product therapy for glucose homeostasis and TIIDM: Sulforaphane, found in Broccoli sprouts and Cauliflower, increases Pax6 and insulin expression, decreases the levels of glucagon, ghrelin and Somatostatin, reduces metabolic stress, improves insulin sensisitity, promotes glucose homeostasis and prevents progression to TIIDM via down regulation of its target gene, 13/January/2017, 11.01 pm

Introduction: What they say A study from the Department of Developmental Biology and Cancer Research, The Institute for Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, […]
January 13, 2017

Natural product-derived combination therapy for augmenting the anti-cancer drug 5-FU (5-Flurouracil) sensitivity in Human cancers: Guttiferone K (GUTK), found in Garcinia cambogia, decreases the expression of the rate-limiting enzyme of the ‘uracil catabolic pathway’ Dihydropyrimidine dehydrogenase (DPYD), increases 5-FU accumulation in cancer cells, augments chemosensitivity, and anti-tumor effect via upregulation of its target gene, 13/January/2017, 10.31 pm

From Research findings to Therapeutic opportunity:  The study presented here suggests that Guttiferone K (GUTK), by increasing the expression of its target genes, it may: (i) decrease the […]
January 13, 2017

Anticancer therapy: MiRNA-9600 increases the expression of tumor suppressor Interleukin-1β (IL-1β), inhibits proliferation, and promotes apoptosis of cancer cells via down regulation of its target gene, 13/January/2016, 10.26 pm

Research findings to Therapeutic opportunity:   The study presented here suggests that MiRNA-9600, by decreasing the expression of its target genes, it may increase the expression of Interleukin-1β (IL-1β). [easy_payment […]
January 13, 2017

Natural product-derived Life-extension therapy: Sauchinone, an antioxidant lignan found in Saururus chinensis, inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span, 13/January/2017, 10.19 am

What they say?  A study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows that “Ribosomal […]
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