Bio-Med Ideas

February 4, 2017
Published by admin_auro at February 4, 2017
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Natural product therapy for Breast Cancer: Scoparone, found in Yin-chen-Saatgut-artemisia-scoparia, increases the level of tumor suppressor p53, decreases the expression of metastasis promoter Snail1, inhibits the proliferation of tumor-initiating cells, suppresses the progression of metastatic breast cancer, and supports tumor relapse-free survival in breast cancer patients, 4/February/2017, 11.59 pm

Introduction: What they say:  A study from the Division of Molecular Medicine and Genetics, Department of Internal Medicine, The Life Sciences Institute, University of Michigan, Ann […]
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February 4, 2017
Published by admin_auro at February 4, 2017
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Natural product-derived therapy for triple-negative breast tumors: American ginseng increases the levels of cell cycle inhibitor, p27, inhibits pro-survival pathways mediated by c-Myc, and inhibits the progression of triple-negative breast cancer via up-regulation of its target gene, 4/February/2016, 11.42 pm

Introduction: What they say  A study from the Department of Cell and Tissue Biology, University of California, San Francisco (UCSF), San Francisco, California, USA shows that […]
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February 4, 2017
Published by admin_auro at February 4, 2017
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Molecular therapy for N-Myc-overexpressing tumors: Cucurbitacin D, found in Trichosanthes kirilowii (Gualou), Phormium tenax, and Luffa amara among others, increases the levels of tumor suppressor proteins, TAp63, TAp63 and Fbw7 (SCF Fbw7 ubiquitin ligase), inhibits the expression of pro-survival proteins N-Myc, Cyclin-E and Mcl-1, and stalls the progression of N-Myc-overexpressing cancers via down regulation of its target gene, 4/February/2017, 11.25 pm

Introduction: What they say A study from the Zhongnan Hospital of Wuhan University, Wuhan 430071, China; and Medical Research Institute, Wuhan University, Wuhan 430071, China shows […]
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February 4, 2017
Published by admin_auro at February 4, 2017
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Natural product-derived PD-1 pathway blockade for Human cancer therapy: Genistein, found in Soy and Amur (Maackia amurensis) among others, inhibits the expression of co-inhibitory receptor PD-1 on Antigen- Specific T-cells, increases the production of cytokines by tumor-infiltrating lymphocytes (TIL), and draining lymph nodes and augments anti-tumor activity via down-regulation of its target gene, 4/February/2017, 11.16 pm

Introduction:What they say: A recent study from Division of Infectious Diseases, School of Medicine, Johns Hopkins University, Baltimore, MD 21218, United States shows that “TGF-β1-Mediated Smad3 […]
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