Bio-Med Ideas

March 6, 2019

Anti-infective Therapy:  Troglitazone (brand name: Rezulin, Resulin, Romozin, Noscal), an anti-hyperglycemic drug, inhibits Hepatitis-B/C, Dengue, Zika, Ebola, HIV-1, Mtb, Malaria, CMV, Influenza H1NI1,  respiratory syncytial,  Sindbis, and SFV viruses by increasing the Levels of the Antiviral Proteins IFITM3, & Interferon-stimulated gene 15, 6/March/2018,  10.19 pm

Introduction: What they say: A study from the Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard Medical School, Charlestown, MA 02129, USA […]
March 6, 2019

Molecular therapy for Pulmonary arterial hypertension: Lactolose (brand name: Cholac, Generlac, Consulose, Duphalac, others) inhibits the development of pulmonary arterial hypertension (PAH) via down-regulation of its target gene Notch3, 6/March/2019, 9.41 pm

What they say:   A study from the University of California, La Jolla, California, USA shows that “Notch3 signaling promotes the development of pulmonary arterial hypertension.” This study was published, in the 15 November  2009 issue of the journal “Nature Medicine“[the number […]
March 5, 2019

Probiotic-based therapy for lowering cholesterol, and triglycerides levels: Lactobacillus rhamnosus GG (LGG) decreases the levels of HMGCR,  triglycerides, free cholesterol, and total cholesterol and prevents the progression of Non-alcoholic fatty liver disease (NAFLD), via up-regulation of its target gene, 5/March/2019, 6.41 pm

The significance of the study: Given that: (1)  15-30% of Western populations suffer from Non-alcoholic fatty liver disease (NAFLD), while 6-25% of Asian populations suffer from it; (2) 75 […]
March 5, 2019

Probiotic-based therapy for diabetes: Probiotic bifidobacterium CECT 7765  increases the expression of IGF1R, INSR, and IRS2, and promotes an insulin-sensitized state, via up-regulation of  its target gene Lin28, 5/March/2019, 6.35 pm

 Introduction: What they say:   A study from the Stem Cell Transplantation Program, Division of Pediatric Hematology/Oncology, Boston Children’s Hospital and Dana-Farber Cancer Institute, Boston, Massachusetts, USA shows that “The Lin28/let-7 axis […]
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