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Idea Proposed/Formulated byDr L Boominathan Ph.D.

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CitationBoominathan, Insights into molecular mechanisms that drive  hyperglycemia and T2D: E2F3 increases CyclinD1 expression and inhibits gluconeogenesis via transcriptional regulation of Peroxisome proliferator-activated receptor γ coactivator-1α, 15/September/2014, 5.46 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

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Significance: This study suggests that E2F3by decreasing the expression of its target gene, it  may inhibit gluconeogenesis.  Thus, pharmacological formulations encompassing “E2F3 activators” may be used to treat DM.

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