Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
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Citation: Boominathan, Insights into molecular mechanisms that drive hyperglycemia and T2D: Tumor suppressor ING1b suppresses CyclinD1 expression and promotes hyperglycemia via transcriptional regulation of Peroxisome proliferator-activated receptor γ coactivator-1α, 19/September/2014, 7.13 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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Significance: This study suggests that ING1b, by regulating the expression of Peroxisome proliferator-activated receptor γ coactivator-1α, it may promote gluconeogenesis and hyperglycemia. Thus, pharmacological formulations encompassing “ING1b inhibitor” may be used to treat DM.
* Research cooperation