Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
Citation: Boominathan, Insights into the treatment of Fibrosis: Stem cell protein Oct4 suppresses the expression of TGFß receptor II (TGFBR2) and extracellular matrix proteins via up regulation of its target gene, 28/October/2014, 07.32, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/
Significance: This study suggests that Stem cell protein Oct4, by increasing the expression of its target gene, it may decrease the expression of TGFß receptor II (TGFBR2) and extracellular matrix proteins. Thus, pharmacological formulations encompassing “Oct-4 activators“ may be used to treat fibrosis.
Amount: $300
Undisclosed information: An insight into how Oct-4 suppresses the expression of TGFß receptor II (TGFBR2) and extracellular matrix proteins.
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