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  • A study from the Department of Cardiology, Boston Children’s Hospital, Harvard Medical School, Cambridge, MA, USA has reported that “Mir-17-92 cluster is required for and sufficient to induce cardiomyocyte proliferation in postnatal and adult hearts.”
  • This study was published in the 09 May 2014 Circulation Research by Prof. Wang and others from the Department of Cardiology, Boston Children’s Hospital, Harvard Medical School, Cambridge, MA, USA.
  • On the foundation of this interesting finding, Dr L Boominathan, Director-cum-chief Scientist of GBMD, reports here that: Insights into the treatment of Myocardial disorders: Pitx2 promotes myocardial proliferation in postnatal and adult hearts via up regulation of its target gene. This study suggests that Pitx2, by suppressing the expression of its target gene, it could promote myocardial proliferation and cardiac regeneration.  Together, this study suggests that pharmacological formulations containing “Pitx2 or Pitx2 activators” can be used to promote cardiac regeneration

Idea Proposed/Formulated by: Dr L Boominathan Ph.D.

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To citeBoominathan, Insights into the treatment of Myocardial disorders: Pitx2 promotes myocardial proliferation in postnatal and adult hearts via up regulation of its target gene, 5/June/2014, 6.09 am,  Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

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