- A study from the Department of Pharmacology, Rush University Medical Center, Rush University, Chicago, IL, USA has reported that “MicroRNA expression profile and functional analysis reveal that miR-382 is a critical novel gene of alcohol addiction”
- This study was published in the 05 September 2013 EMBO Molecular Medicine by Prof. Zhang C, Dr. Li J, and others from the Department of Pharmacology, Rush University Medical Center, Rush University, Chicago, IL, USA.
- On the foundation of this interesting finding, Dr L Boominathan, Director-cum-chief Scientist of GBMD, reports here that: p53 inhibitor-based treatment for Stress-induced alcohol addiction: Stress induced gene product p53 increases the expression of DRD1 via up regulation of its target gene . This study suggests that Emotional/Mental/Physical stress-induced gene product p53, by increasing the expression of its target gene, it could augment voluntary intake of alcohol and alcohol addiction. Together, this study suggests that pharmacological formulations containing “ p53 inhibitors” can be used to treat alcohol addiction .
Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
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To cite: Boominathan, p53 inhibitor-based treatment for Stress-induced alcohol addiction: Stress induced gene product p53 increases the expression of DRD1 via up regulation of its target gene, 18/June/2014, 5.40 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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