Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
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Citation: Boominathan, Insights into the treatment of Stress-induced T2D: MiR-125b increases the expression of a positive regulator of insulin transcription, NeuroD1 via down regulation of its target gene, 28/August/2014, 08.10 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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Significance: Prolonged physical/mental/emotional/environmental stress can induce the expression of a number of stress-responsive proteins. This study suggests, for the first time, that miR-125b, by decreasing the expression of a number of stress responsive proteins, it may increase the expression of an activator of insulin transcription, NeuroD1. This data suggests that “miR-125b activators” may be used to treat stress-induced T2D.