Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
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Citation: Boominathan, Interlekin-mediated tumor suppression: IL-1β suppresses the expression of a negative regulator of p53 HDM2 via up regulation of its target gene, 24/September/2014, 06.48 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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Significance: This study suggests that IL-1β, by increasing the expression of its target gene, it may decrease HDM2. Thereby, it may function as a tumor suppressor. Thus, pharmacological formulations encompassing “IL-1β or its activator” may be used to inhibit tumor progression.
* Research cooperation
