Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/
Citation: Boominathan, Mechanistic insight into interleukin-mediated tumorigenesis: Interleukin-17 (IL-17) decreases the stability and activity of p73α and promotes tumorigenesis via down regulation of its target gene, 17/January/2015, 21.23, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
Significance: This study suggests, for the first time, that IL-17, by increasing the expression of its target gene, it may decrease the stability and activity of tumor suppressor p53 homologue p73α. Thereby, it may promote tumorigenesis. Thus, pharmacological formulations encompassing “IL-17 inhibitors” can be used to inhibit the progression of human tumors, including p53-mutated human tumors.
Amount: $ 300
Undisclosed information: How IL-17 increases the stability and activity of p73α
Web: http://genomediscovery.org
Courtesy: When you cite drop us a line at info@genomediscovery.org
* Research cooperation