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Idea Proposed/Formulated byDr L Boominathan Ph.D.

CitationBoominathan, Interleukin-based therapy for Fibrosis: IL-1β suppresses the expression of TGFß receptor II (TGFBR2) and extracellular matrix proteins via up regulation of its target gene, 25/October/2014, 10.44 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/

Significance: This study suggests that IL-1β, by increasing the expression of its target gene,  it may decrease the expression of TGFß receptor II (TGFBR2) and extracellular matrix proteins. Thus, pharmacological formulations encompassing IL-1β activators may be used to treat fibrosis.

Amount: $300

Undisclosed information: An insight into how IL-1β suppresses the expression of TGFß receptor II (TGFBR2)  and extracellular matrix proteins.

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