Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
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Citation: Boominathan, Interleukin-mediated metastatic tumor suppression: Pro-inflammatory cytokine IL-1β increases the expression of tumor suppressor p53/p73 and inhibits metasatic progression via up regulation of its target gene, 23/September/2014, 06.50 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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Significance: This study suggests that IL-1β, by increasing the expression of its target gene, it may increase the expression of tumor suppressor p53/p73. Thereby, it may function as a metastasis suppressor. Thus, pharmacological formulations encompassing “IL-1β or its activator” may be used to inhibit tumor metastasis.
* Research cooperation