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  • A study from the State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100049, China etc., has reported that “Atg7 is required for acrosome biogenesis during spermatogenesis in mice.

  • This study was published in the 23 May 2014 Cell Reports by Prof. Li W and Wang H, and others from the State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China;  University of Chinese Academy of Sciences, Beijing 100049, China etc..

  • On the foundation of this interesting finding, Dr L Boominathan, Director-cum-chief Scientist of GBMD, reports here that:  Mechanistic and Therapeutic insights into the treatment of Globozoospermia: MiRNA-17 regulates Acrosome biogenesis during Spermatogenesis via down regulation of its target geneThis study suggests that MiRNA-17, by decreasing the expression of its target gene, it could regulate Acrosome biogenesis during Spermatogenesis.  Taken together, this study suggests that pharmacological formulations containing “MiRNA-17 regulator” can be used to treat Globozoospermia.
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Idea Proposed/Formulated by: Dr L Boominathan Ph.D.

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To citeBoominathan, Mechanistic and Therapeutic insights into the treatment of Globozoospermia: MiRNA-17 regulates Acrosome biogenesis during Spermatogenesis via down regulation of its target gene, 13/July/2014, 6.50 am,  Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

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