- A study from the State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100049, China etc., has reported that “Atg7 is required for acrosome biogenesis during spermatogenesis in mice.”
- This study was published in the 23 May 2014 Cell Reports by Prof. Li W and Wang H, and others from the State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100049, China etc..
- On the foundation of this interesting finding, Dr L Boominathan, Director-cum-chief Scientist of GBMD, reports here that: Mechanistic and Therapeutic insights into the treatment of Globozoospermia: MiRNA-290-295 cluster regulates Acrosome biogenesis during Spermatogenesis. This study suggests that MiRNA-290-295, by decreasing the expression of its target gene, it could regulate Acrosome biogenesis during Spermatogenesis. Taken together, this study suggests that pharmacological formulations containing “MiRNA-290-295 regulator” can be used to treat Globozoospermia.
Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
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To cite: Boominathan, Mechanistic and Therapeutic insights into the treatment of Globozoospermia: MiRNA-290-295 cluster regulates Acrosome biogenesis during Spermatogenesis, 12/July/2014, 5.44 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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