Mechanistic and therapeutic insights into Vascular Constriction: Tumor suppressor PTEN promotes Endothelium-dependent vascular constriction via up regulation of its target gene, 16/October/2014, 6.29 am

Mechanistic and therapeutic insights into Vascular Constriction: Tumor suppressor PTEN promotes Endothelium-dependent vascular constriction via up regulation of its target gene, 16/October/2014, 6.29 am

Mechanistic and therapeutic insights into Vascular Constriction: Tumor suppressor PTEN promotes Endothelium-dependent vascular constriction via up regulation of its target gene, 16/October/2014, 6.29 am 150 150 Dr Boomi's Genom-2-Discovery Center

Idea Proposed/Formulated byDr L Boominathan Ph.D.

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To citeBoominathan, Mechanistic and therapeutic insights  into Vascular Constriction: Tumor suppressor PTEN  promotes Endothelium-dependent vascular constriction via up regulation of its target gene, 16/October/2014, 6.29 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

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Significance: This study suggests that stress-induced PTENby increasing the expression of its target gene, it may promote Vascular constriction. Together, this study suggests that pharmacological formulations encompassing “PTEN  inhibitors” may be used to treat pathological situations associated with vascular constriction.