Mechanistic and Therapeutic insights into Vascular endothelial senescence and Arterial stiffness: MiRNA-142 inhibits endotheilial function and increases arterial stiffness via down regulation of its target gene, 11/October/2014, 23.15

Idea Proposed/Formulated by: Dr L Boominathan Ph.D.

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To cite: Boominathan, Mechanistic and Therapeutic insights into Vascular endothelial senescence and Arterial stiffness: MiRNA-142 inhibits endotheilial function and increases arterial stiffness via down regulation of its target gene, 11/October/2014, 23.15, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

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Significance: This study suggests that stress-induced miRNA-142, by suppressing the expression of its target gene, it may promote Vascular endothelial senescence and Arterial stiffness. Together, pharmacological formulations encompassing “MiRNA-142 activators” may be used to treat endothelial dysfunction and arterial stiffness.