Mechanistic insight into Interleukin-mediated tumorigenesis: IL-17 increases the expression of oncogenic protein MDM2, a negative regulator of p53, via down regulation of its target gene, 13/February/2015, 22.00

Mechanistic insight into Interleukin-mediated tumorigenesis: IL-17 increases the expression of oncogenic protein MDM2, a negative regulator of p53, via down regulation of its target gene, 13/February/2015, 22.00

Mechanistic insight into Interleukin-mediated tumorigenesis: IL-17 increases the expression of oncogenic protein MDM2, a negative regulator of p53, via down regulation of its target gene, 13/February/2015, 22.00 150 150 Dr Boomi's Genom-2-Discovery Center

Idea Proposed/Formulated by: Dr L Boominathan Ph.D.

Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/

Citation: Boominathan, Mechanistic insight into Interleukin-mediated tumorigenesis: IL-17 increases the expression of oncogenic protein MDM2, a negative regulator of p53, via down regulation of its target gene, 13/February/2015, 22.00, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

Significance: This study suggests that IL-17, by decreasing the expression of its target gene, it may increase the expression of MDM2.  Thereby, it may promote the degradation of tumor suppressor p53 and initiate tumorigenesis. Thus, pharmacological formulations encompassing “IL-17 inhibitors“  may be used to inhibit the proliferation of cancer cells.

Amount: $ 500*

Undisclosed information: How IL-17 increases the expression of MDM2

Web: http://genomediscovery.org

Courtesy: When you cite drop us a line at info@genomediscovery.org

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