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Idea Proposed/Formulated byDr L Boominathan Ph.D.

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CitationBoominathan, Interleukin-based therapy for Metastatic tumors:  IL-17 increases the expression of PD-1 , a suppressor of activation of T-cells, via up regulation of its target gene, 15/February/2015, 22.53, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

Significance: This study suggests that IL-17, by increasing the expression of its target gene, it may increase the expression of PD-1.  Thereby, it may suppress the immune system that attack tumors and promote metastasis. Thus, pharmacological formulations encompassing “IL-17 inhibitors  may be used to inhibit the progression of tumors.

Amount: $ 300*

Undisclosed information: How IL-17 increases the expression of PD-1

Web: http://genomediscovery.org

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