Mechanistic insight into Regulation of Ribosome biogenesis: Resistin suppresses the expression of RNA polymerase I via down regulation of its target gene, 23/February/2015, 22.36

Mechanistic insight into Regulation of Ribosome biogenesis: Resistin suppresses the expression of RNA polymerase I via down regulation of its target gene, 23/February/2015, 22.36

Mechanistic insight into Regulation of Ribosome biogenesis: Resistin suppresses the expression of RNA polymerase I via down regulation of its target gene, 23/February/2015, 22.36 150 150 Dr Boomi's Genom-2-Discovery Center

Idea Proposed/Formulated byDr L Boominathan Ph.D.

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CitationBoominathan, Mechanistic insight into Regulation of Ribosome biogenesis: Resistin suppresses the expression of RNA polymerase I via down regulation of its target gene, 23/February/2015, 22.36, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

Significance: This study suggests, for the first time, that Resistin, by increasing the expression of  its target gene, it may decrease the expression of RNA polymerase I. Thereby, it may inhibit the proliferation of cancer cells. Thus, pharmacological formulations encompassing “Resistin activators”  can be used to inhibit the progression of human cancers. 

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* Research cooperation

Undisclosed information: How Resistin suppresses the expression of RNA polymerase I

Amount: $ 300