Mechanistic insight into tumor suppression: Demethylase JMJD3 suppresses the expression of actin-regulatory proteins FHOD1 and PPM1F and inhibits migration and invasion of metastatic cancer cells via up regulation of its target gene, 19/March/2015, 22.11

Mechanistic insight into tumor suppression: Demethylase JMJD3 suppresses the expression of actin-regulatory proteins FHOD1 and PPM1F and inhibits migration and invasion of metastatic cancer cells via up regulation of its target gene, 19/March/2015, 22.11

Mechanistic insight into tumor suppression: Demethylase JMJD3 suppresses the expression of actin-regulatory proteins FHOD1 and PPM1F and inhibits migration and invasion of metastatic cancer cells via up regulation of its target gene, 19/March/2015, 22.11 150 150 Dr Boomi's Genom-2-Discovery Center

Idea Proposed/Formulated by: Dr L Boominathan Ph.D.

Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/

Citation: Boominathan, L., Mechanistic insight into tumor suppression: Demethylase JMJD3 suppresses the expression of actin-regulatory proteins FHOD1 and PPM1F and inhibits migration and invasion of metastatic cancer cells via up regulation of its target gene, 19/March/2015, 22.11, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

Significance: The study presented here suggests that JMJD3, by increasing the expression of its target gene, it may suppress the expression of actin-regulatory proteins FHOD1 and PPM1F. Thereby, it may inhibit migration and invasion of metastatic cancer cells. Thus, pharmacological formulations encompassing “JMJD3 activators” may be used to inhibit the progression of invasive tumors.

Amount: $ 500*

Undisclosed information: How JMJD3 decreases the expression of FHOD1 and PPM1F

Web: http://genomediscovery.org

Courtesy: When you cite drop us a line at info@genomediscovery.org

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