Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
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Citation: Boominathan, Mechanistic insights into tumorigenesis: SNAI2 increases the expression of stem cell protein Sox2 via up regulation of its target gene, 30/September/2014, 04.57 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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Significance: This study suggests that SNAI2, by increasing the expression of its target gene, it may promote: (1) drug resistance; and (2) tumor cell proliferation. Thus, this study suggests that pharmacological formulations encompassing “SNAI2 inhibitor” may be used to (1) increase drug sensitivity; (2) and inhibit tumor proliferation.