- A study from the Departments of Anesthesiology and Neurobiology, Duke University Medical Center, Durham, NC 27710, USA has reported that “Extracellular MicroRNAs Activate Nociceptor Neurons to Elicit Pain via….”
- This study was published in the 02 April 2014 Neuron by Prof. Ji RR, Park CK and others from the Departments of Anesthesiology and Neurobiology, Duke University Medical Center, Durham, NC 27710, USA.
- On the foundation of this interesting finding, Dr L Boominathan, Director-cum-chief Scientist of GBMD, reports here that: Mechanistic & Therapeutic insights into the regulation of pain responses: RREB inhibits pain responses via down regulation of cation channel transient receptor potential A1. This study suggests that RREB, by suppressing the expression of its target gene, it could inhibit pain responses. Together, this study suggests that pharmacological formulations containing “RREB or RREB activating small molecules” can be used to alleviate pain responses.
Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
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To cite: Boominathan, Mechanistic & Therapeutic insights into the regulation of pain responses: RREB [Ras responsive element (RRE) binding protein] inhibits pain responses via down regulation of cation channel transient receptor potential A1, 14/June/2014, 7.09 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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