Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
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Citation: Boominathan, MiRNA-based Anti-ageing therapy: Argonaute2 (AGO2) increases the expression of immortality gene telomerase via down regulation of its target genes, 8/June/2015, 12. 16 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
Significance: It has been shown earlier that transgenic expression of telomerase increases the longevity of mice. This study suggests, for the first time, that Argonaute2 (AGO2), by decreasing the expression of its target gene, it may increase the expression of immortality gene telomerase. Thereby, it may increase the life-span of an individual. Thus, pharmacological formulations encompassing “Argonaute2 (AGO2) activators” can be used to decrease ageing and increase the life-span of an individual.
Undisclosed information: How Argonaute2 (AGO2) increases the expression of immortality gene telomerase
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