On the eve of Mahatma Gandhi Birth Anniversary
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We wish everyone a happy Mahatma Gandhi Jayanti 2014. On this special occasion, we are happy to announce that Ideas posted today (02/October/2014) will be available to the use of Scientists/Professors/Physicians/Researchers for free. So, there will be no terms and conditions for the ideas posted today (02/October/2014). Each idea posted will be served first come, first served basis. For more details, you may write to us at info@genomediscovery.org
Dr L Boominathan PhD
CEO & CSO, GBMD
A study from the Department of Molecular Biology, Princeton University, Princeton, New Jersey 08544, USA shows that “ΔNp63 promotes stem cell activity in mammary gland development and basal-like breast cancer by enhancing Fzd7 expression and Wnt signalling.”
This study was published in the September issue of 2014 Nature Cell Biology (I.F: 20.085) by Dr. Kang Y, Rumela Chakrabarti [I.F > 20.058] and others from the Princeton University, New Jersey 08544, USA
On the foundation of this interesting finding, Dr L Boominathan, Director-cum-chief Scientist of GBMD, reports here that: MiRNA-based Anti-cancer stem cell therapeutics: MiRNA-29 inhibits mammary cancer stem cell proliferation via down regulation of Wnt receptor FZD7. This study may suggest that MiRNA-29, by down regulating its target gene, it may inhibit the Wnt pathway. Together, this study suggests that pharmacological formulations encompassing “MiRNA-29 or its activators“ can be used to inhibit tumor initiating mammary cancer cells.
Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
Web: http://genomediscovery.org
Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/
To cite: Boominathan, L., MiRNA-based Anti-cancer stem cell therapeutics: MiRNA-29 inhibits mammary cancer stem cell proliferation via down regulation of Wnt receptor FZD7, 02/October/2014, 16.48, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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