Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/
Citation: Boominathan, MiRNA-based anticancer therapy: Tumor suppressor MiRNA-429 increases the expression of cell cycle inhibitor INK4b/p15 via down regulation of its target genes, 19/February/2015, 21.44, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
Significance: This study suggests, for the first time, that tumor suppressor MiRNA-429, by decreasing the expression of its target gene, it may increase the expression of INK4b/p15. Thereby, it may inhibit the proliferation of cancer cells. Thus, pharmacological formulations encompassing “MiRNA-429 activators” can be used to inhibit the progression of human cancers.
Amount: $ 300
Undisclosed information: How MiRNA-429 increases the expression of p15(INK4b).
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* Research cooperation