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Idea Proposed/Formulated byDr L Boominathan Ph.D.

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CitationBoominathan, MiRNA-based cancer therapeutics: MiRNA-146b-5p increases the expression of tumor suppressor p53 and its homolouge p73 via down regulation of its target gene, 01/October/2014, 07.48 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

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Significance: It has recently been shown that MiRNA-146b-5p functions as a tumor- and metastasis suppressorThis study suggests that MiRNA-146-5p, by decreasing the expression of its target gene, it may increase the expression of p53 and p73.   Thus, this study suggests that pharmacological formulations encompassing MiRNA-146-5p or its activators” may be used to treat human cancers.

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