A study from the Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, USA has reported that excessive TGF-β signaling is a common mechanism in osteogenesis imperfecta.
This study was published in the 04 May 2014 Nature Medicine (IF-24.3) by Prof. Brendan Lee, Dr Ingo Grafe and others from Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, USA; Department of Orthopaedic Surgery, University of Texas Health Science Center at Houston, Houston, Texas, USA etc.
On the foundation of this interesting finding, Dr L Boominathan, Director-cum-chief Scientist of GBMD, reports here that: MiRNA-based therapy for brittle bones, fractures and extraskeletal manifestations: MiRNA-101 ameliorates osteogenesis imperfecta (OI) via down regulation of its target gene
Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
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To cite: Boominathan, MiRNA-based therapy for brittle bones, fractures and extraskeletal manifestations: MiRNA-101 ameliorates osteogenesis imperfecta (OI) via down regulation of its target gene, 23/May/2014, 9.33 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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