Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
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Citation: Boominathan, MiRNA-based therapy for Cancer: MIRNA-134 decreases the expression of immortality-associated gene product telomerase via down regulation of its target gene, 22/September/2014, 08.49 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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Significance: This study suggests that MIRNA-134 inhibits the expression of immortality gene telomerase. Thus, pharmacological formulations encompassing “MIRNA-134 or MiRNA-134 activators” may be used to inhibit cancer progression. Further, pharmacological formulations encompassing “AntagomiR-134 or MiRNA-134 inhibitors” may be used to (1) deaccelerate ageing/senescence process; and (2) increase the longevity of an individual.
* Research cooperation