MiRNA-based therapy for Cancer and ageing: MIRNA-134 increases the expression of tumor suppressor INK4a/p16 via down regulation of its target gene, 23/September/2014, 07.43 am

MiRNA-based therapy for Cancer and ageing: MIRNA-134 increases the expression of tumor suppressor INK4a/p16 via down regulation of its target gene, 23/September/2014, 07.43 am

MiRNA-based therapy for Cancer and ageing: MIRNA-134 increases the expression of tumor suppressor INK4a/p16 via down regulation of its target gene, 23/September/2014, 07.43 am 150 150 Dr Boomi's Genom-2-Discovery Center

Idea Proposed/Formulated byDr L Boominathan Ph.D.

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CitationBoominathan, MiRNA-based therapy for Cancer and ageing: MIRNA-134 increases the expression of tumor suppressor INK4a/p16 via down regulation of its target gene, 23/September/2014, 07.43 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

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Significance: This study suggests that MIRNA-134 increases the expression of tumor suppressor INK4a/p16. Thus, pharmacological formulations encompassing MIRNA-134 or MiRNA-134 activators” may be used to inhibit cancer progression.  Further, pharmacological formulations encompassing “AntagomiR-134 or MiRNA-134 inhibitors” may be used to deaccelerate ageing/senescence process.

* Research cooperation