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Idea Proposed/Formulated byDr L Boominathan Ph.D.

CitationBoominathan, MiRNA-based therapy for Cancer: MiRNA-128 inhibits proliferation and promotes senescence through up regulation of tumor suppressor LKB1, 29/October/2014, 05.23 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

Significance: This study suggests that tumor suppressor MiRNA-128, by decreasing the expression of its target gene, it may increase the expression of tumor suppressor LKB1. Thus, pharmacological formulations encompassing “MiRNA-128 or its activators may be used to treat LKB1-mutated human tumors.

Undisclosed information: A mechanistic insight into how MiRNA-128 increases the expression of  LKB1.

Amount: $ 300

Web: http://genomediscovery.org

Courtesy: When you cite drop us a line at info@genomediscovery.org

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