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Idea Proposed/Formulated byDr L Boominathan Ph.D.

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CitationBoominathan, MiRNA-based therapy for Cancer: MIRNA-190b increases the expression of tumor suppressor p53 via down regulation of its target gene, 22/September/2014, 22.59, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

Significance: p53 is the most mutated gene in human cancer.  MIRNA-190b, by suppressing the expression of its target gene, it could induce the expression of p53.  Thus, pharmacological formulations encompassing “MIRNA-190b” can be used to treat human cancers. 

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