Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
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Citation: Boominathan, MiRNA-based therapy for Cancer: MIRNA-190b increases the expression of tumor suppressor p53 via down regulation of its target gene, 22/September/2014, 22.59, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
Significance: p53 is the most mutated gene in human cancer. MIRNA-190b, by suppressing the expression of its target gene, it could induce the expression of p53. Thus, pharmacological formulations encompassing “MIRNA-190b” can be used to treat human cancers.
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* Research cooperation