Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
Citation: Boominathan,MiRNA-based therapy for Cancer: MiRNA-217 inhibits proliferation and promotes senescence through up regulation of tumor suppressor LKB1, 16/October/2014, 06.26 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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Significance: This study suggests that tumor suppressor MiRNA-217, by decreasing the expression of its target gene, it may increase the expression of tumor suppressor LKB1. Thus, pharmacological formulations encompassing “MiRNA-217 or its activators“ may be used to treat LKB1-mutated human tumors.